Breast Cancer Specific miRNA-mRNA Binding Region Analysis using Signal Processing Techniques

Conference: Recent Application and Trends in Modern Engineering
Author(s): Binthiya Suny Gabriel, Tessamma Thomas Year: 2018
Grenze ID: 02.RATME.2018.1.6_1 Page: 120-138

Abstract

A new approach for identifying the binding region between the\nmiRNA and mRNA using the STFT method with Blackman window of length 24\nis presented in this paper. The seed region within the miRNA is also identified\nusing simple correlation methods. mRNA, RAC3 GTPase, is used for the\nanalysis. Results of binding region and seed region identification based on the\nmethods mentioned above, provide values closest to the data available at\nMicrocosm website.

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RATME - 2018